Row 28703

Row ID: 28703 | Dataset Entry | Axioma AXP Content Repository

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I’m one of the few people who actually has first hand experience with this. I built and surgically implanted electrodes into rat brains. I can say for sure that we were working with limited time on the implants due to retraction, or more commonly dura matter healing over the wires. Having large amounts of wires become unusable is not entirely surprising and I’m sure the researchers expected this to some degree. Human dura matter is more durable, and is the thickest of all animals that are practical to study by nearly double. We also have dramatic differences in the arachnoid layer and pia mater coverings to the point they were not even visible and practically irrelevant in the rat model. This explanation seems at least plausible to me, and due to the rather dramatic difference between rat and human brain “coverings” expecting different results in humans is reasonable. I’ve not personally touched human dura but it’s supposedly slightly leathery and very tough. In contrast rat dura is like the finest tissue paper. The difference in mechanical strength alone would be sufficient to think maybe the wires would hold better.

FieldValue
text I’m one of the few people who actually has first hand experience with this. I built and surgically implanted electrodes into rat brains. I can say for sure that we were working with limited time on the implants due to retraction, or more commonly dura matter healing over the wires. Having large amounts of wires become unusable is not entirely surprising and I’m sure the researchers expected this to some degree. Human dura matter is more durable, and is the thickest of all animals that are practi…
label r/technology
dataType comment
communityName r/technology
datetime 2024-05-21
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url_encoded Z0FBQUFBQm5Lak9VU2lFUzBMU3RKdEJKSXZfUlY1aXFxOWxvN2Z5MDA2SFFCZlBFUC0zbEl4Yk1lbmxhM3g0bzhtcXphd3c1b2NOTmY5TS14ZkZEYzFzMWVraU4yNFR5QkRUV1M4MTJrM3pIdDZFRTJudzlTSTBadld0dW1WZVNFd3FDT0YtYlBxZzBQcUNqbVdkOGtWTWp5TXJxdEt5R0t5Sm5zYWhhMjAwNlIwNTgtaW9qckRhY0lFVXROUm9FaDVVNUIwVnpMUmFMQk5DN1hJOThqTjBwX0FaVVF1aHczdz09

Raw Record

{
  "text": "I’m one of the few people who actually has first hand experience with this. I built and surgically implanted electrodes into rat brains. I can say for sure that we were working with limited time on the implants due to retraction, or more commonly dura matter healing over the wires. Having large amounts of wires become unusable is not entirely surprising and I’m sure the researchers expected this to some degree. Human dura matter is more durable, and is the thickest of all animals that are practical to study by nearly double. We also have dramatic differences in the arachnoid layer and pia mater coverings to the point they were not even visible and practically irrelevant in the rat model. This explanation seems at least plausible to me, and due to the rather dramatic difference between rat and human brain “coverings” expecting different results in humans is reasonable. I’ve not personally touched human dura but it’s supposedly slightly leathery and very tough. In contrast rat dura is like the finest tissue paper. The difference in mechanical strength alone would be sufficient to think maybe the wires would hold better.",
  "label": "r/technology",
  "dataType": "comment",
  "communityName": "r/technology",
  "datetime": "2024-05-21",
  "username_encoded": "Z0FBQUFBQm5Lak1FM2NkOFZ1SnNjandWbW1aUkZUS1duWlUySjVWNFlwX2t2a0JMdVZzMTBSVVdRWFFUX0tzUTFCWVdQeWZwXzVpQnptelNyOTFhZm5zMjVpZ0h1VUlmZnc9PQ==",
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}
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