Row 10236

Row ID: 10236 | Dataset Entry | Axioma AXP Content Repository

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This page contains data entry 10236 from the Axioma AXP content repository. The structured data below represents the complete record for this entry.

The article is a little misleading.

Wegovy and its brethren from Novo use the *base* form of the medically active ingredient semaglutide in its Wegovy/Ozempic/Rybelsus products.

Compounders are using a conjugate salt of semaglutide, and NOT the base form. Important note, Novo chose the *base* form over the conjugate *salt*, for it's Wegovy/Ozempic and Rybelsus products.

So the salt form is pharmacologically a different active ingredient than the FDA approved drug, which contain the base form of semaglutide. And there have been no peer reviewed clinical trials conducted on the salt form to determine safety and efficacy.

Amongst other issues, it's believed the molecular size/weight of the salt form presents absorption issues/difficulties, not evidenced with the base form of semaglutide.

FieldValue
text The article is a little misleading. Wegovy and its brethren from Novo use the *base* form of the medically active ingredient semaglutide in its Wegovy/Ozempic/Rybelsus products. Compounders are using a conjugate salt of semaglutide, and NOT the base form. Important note, Novo chose the *base* form over the conjugate *salt*, for it's Wegovy/Ozempic and Rybelsus products. So the salt form is pharmacologically a different active ingredient than the FDA approved drug, which contain the base form …
label r/health
dataType comment
communityName r/Health
datetime 2024-05-20
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url_encoded Z0FBQUFBQm5Lak9JTGw2R3RXNFpYR3c5Z0h5OXc1cE5ZUkEzZng2WF9sMHItTl9rMGpjM2R1ZTNqRFZTMU9ZTmNyZUxJTUw1T0ducU43ajgwUGkyeklDdXAyUENIWlY1Q19IRjBhTDlFUXFXbWZTMHZTWGk1cnpPY3dJNVcwN2pkcEJOZnNmQk91SWxpTlkzQVpEWTJxZHk4VzNkWDRXQ2lycnFibGJNbW9UREk1VGRwNkdJM1FRbnpnSnFHbERvREtNTjVGQ1V5dlhtZmdTVElMMkppVFMyU3RDT285U0liUT09

Raw Record

{
  "text": "The article is a little misleading.\n\nWegovy and its brethren from Novo use the *base* form of the medically active ingredient semaglutide in its Wegovy/Ozempic/Rybelsus products.\n\nCompounders are using a conjugate salt of semaglutide, and NOT the base form. Important note, Novo chose the *base* form over the conjugate *salt*, for it's Wegovy/Ozempic and Rybelsus products.\n\nSo the salt form is pharmacologically a different active ingredient than the FDA approved drug, which contain the base form of semaglutide. And there have been no peer reviewed clinical trials conducted on the salt form to determine safety and efficacy.\n\nAmongst other issues, it's believed the molecular size/weight of the salt form presents absorption issues/difficulties, not evidenced with the base form of semaglutide.",
  "label": "r/health",
  "dataType": "comment",
  "communityName": "r/Health",
  "datetime": "2024-05-20",
  "username_encoded": "Z0FBQUFBQm5Lakw1djRteTJTMHlTal85Y1RhRjlRM0lYVVhkeDdBUVlxemdmQ1Z6OHFQTjJSVllVVVhEcEtiaEd0bjhXc0NiU1pTZV90cDdWcDRMbVF5T3E4R3ozUG40SU5VLWRGVXdOdkpfV25uVVR1aF9PZDg9",
  "url_encoded": "Z0FBQUFBQm5Lak9JTGw2R3RXNFpYR3c5Z0h5OXc1cE5ZUkEzZng2WF9sMHItTl9rMGpjM2R1ZTNqRFZTMU9ZTmNyZUxJTUw1T0ducU43ajgwUGkyeklDdXAyUENIWlY1Q19IRjBhTDlFUXFXbWZTMHZTWGk1cnpPY3dJNVcwN2pkcEJOZnNmQk91SWxpTlkzQVpEWTJxZHk4VzNkWDRXQ2lycnFibGJNbW9UREk1VGRwNkdJM1FRbnpnSnFHbERvREtNTjVGQ1V5dlhtZmdTVElMMkppVFMyU3RDT285U0liUT09"
}
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